October 21, 2003

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Forum October 2003

Background: Development and increasing acceptance of rehabilitation robots as well as advances in technology allow new forms of therapy for patients with neurological disorders. Robot-assisted gait therapy can increase the training duration and the intensity for the patients while reducing the physical strain for the therapist. Optimal training effects during gait therapy generally depend on ap...

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FORUM, October 2003

Advances in information technology (IT) have brought a powerful array of new clinical and management tools to VA medical centers (VAMCs), and continue to change in very fundamental ways how we think about and provide primary care. This is particularly important as VA makes the transition from visit-based primary care management to a model of patient-centered primary care management that monitor...

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Extramural Update October 2003

Background: Epidemiological studies on health effects of air pollution have consistently shown adverse cardiovascular effects. Toxicological studies have provided evidence for thrombogenic effects of particles. A prospective panel study in a susceptible population was conducted in Erfurt, Germany, to study the effects of daily changes in ambient particles on various blood cells and soluble CD40...

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NIEHS News October 2003

Background: Hereditary Inclusion Body Myopathy (HIBM) is an autosomal recessive, adult onset, non-inflammatory neuromuscular disorder with no effective treatment. The causative gene, GNE, codes for UDP-N-acetylglucosamine 2epimerase/N-acetylmannosamine kinase, which catalyzes the first two reactions in the synthesis of sialic acid. Reduced sialylation of muscle glycoproteins, such as α-dystrogl...

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Science Selections October 2003

Background: An important mechanism for gene regulation utilizes small non-coding RNAs called microRNAs (miRNAs). These small RNAs play important roles in tissue development, cell differentiation and proliferation, lipid and fat metabolism, stem cells, exocytosis, diseases and cancers. To date, relatively little is known about functions of miRNAs in the lung except lung cancer. Results: In this ...

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ژورنال

عنوان ژورنال: Circulation

سال: 2003

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circ.108.16.1911